PRL
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Application Notes
ELISA. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Reconstitution
Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL
Buffer
0.01 M PBS, pH 7.2
Storage
-20 °C
Storage Comment
Prior to and following reconstitution store the antibody at -20 °C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Expiry Date
12 months
Target
Prolactin (PRL)
Alternative Name
Prolactin / PRL
Background
Prolactin (PRL) is primarily secreted by pituitary gland. The hormone stimulates mammary gland development during pregnancy and lactation after childbirth. PRL has several variations with molecular weights ranged from 22 kDa to 150 kDa. PRL receptors are mainly located at mammary glands, and also found in other organs and tissues. PRL can bind to cytokine-like receptors and influence haematopoiesis, angiogenesis, and immuno-system. Anterior pituitary tumours can cause persistent elevation of PRL with clinical signs such as abnormal lactation, infertility and lack of menstrual flow in women, and incompetence in men.