CGA antibody

Catalog No. ABIN452635

This Mouse Monoclonal antibody specifically detects CGA in EIA and ELISA (Capture). It exhibits reactivity toward Human.

Quick Overview for CGA antibody (ABIN452635)

Target: CGA (Glycoprotein Hormones, alpha Polypeptide (CGA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CGA antibody is un-conjugated

Application: Enzyme Immunoassay (EIA), ELISA (Capture)

Clone: TSH-1

Product Details anti-CGA Antibody

Specificity: This antibody is reactive to Alpha chain of Human TSH.

Characteristics: Synonyms: Follitropin alpha chain, Follicle-stimulating hormone alpha chain, FSH-alpha, Lutropinalpha chain, Luteinizing hormone alpha chain, LSH-alpha, LH alpha, Thyrotropin alphachain, Thyroid-stimulating hormone alpha chain, TSH-alpha, Choriogonadotropin alphachain, Chorionic gonadotrophin subunit alpha, hCG-alpha, Anterior pituitary glycoproteinhormones common subunit alpha

Purification: Affinity Chromatography on Protein G

Immunogen: Human TSH

Isotype: IgG1

Application Details

Application Notes: ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL.

Buffer: 0.01 M PBS, pH 7.2 without preservatives

Preservative: Without preservative

Storage: -20 °C

Storage Comment: Prior to and following reconstitution store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for CGA

Target: CGA (Glycoprotein Hormones, alpha Polypeptide (CGA))

Alternative Name: Glycoprotein Hormones alpha Chain

Background: Thyroid stimulating hormone (TSH), also known as thyrotropin, is secreted from cells in the anterior pituitary called thyrotrophs, finds its receptors on epithelial cells in the thyroid gland, and stimulates that gland to synthesize and release thyroid hormones. TSH is a glycoprotein hormone composed of two subunits which are non covalently bound to one another. The alpha subunit of TSH is also present in two other pituitary glycoprotein hormones, follicle stimulating hormone and luteinizing hormone, and, in primates, in the placental hormone chorionic gonadotropin. Each of these hormones also has a unique beta subunit, which provides receptor specificity. In other words, TSH is composed of alpha subunit bound to the TSH beta subunit, and TSH associates only with its own receptor. Free alpha and beta subunits have essentially no biological activity. TSH has a alpha subunit that is identical to the one in other glycoprotein hormones such as LH, FSH and HCG.Synonyms: Anterior pituitary glycoprotein hormones common subunit alpha, Choriogonadotropin alpha chain, Chorionic gonadotrophin subunit alpha, FSH-alpha, Follicle-stimulating hormone alpha chain, Follitropin alpha chain, LH alpha, LSH-alpha, Luteinizing hormone alpha chain, Lutropin alpha chain, TSH-alpha, Thyroid-stimulating hormone alpha chain, Thyrotropin alpha chain, hCG-alpha

Gene ID: 1081

UniProt: P01215

Pathways: Metabolism of Steroid Hormones and Vitamin D, Thyroid Hormone Synthesis, Hormone Transport, Peptide Hormone Metabolism