TSHB antibody (HRP)
Quick Overview for TSHB antibody (HRP) (ABIN452636)
Target
See all TSHB AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- This antibody is reactive to beta chain of Human TSH
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Purification
- Affinity Chromatography on Protein G
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Isotype
- IgG1
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 50 % 0.01 M PBS, pH 7.2 and 50 % Glycerol
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- TSHB (Thyroid Stimulating Hormone, beta (TSHB))
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Alternative Name
- Thyrotropin beta Chain
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Background
- Thyroid stimulating hormone (TSH), also known as thyrotropin, is secreted from cells in the anterior pituitary called thyrotrophs, finds its receptors on epithelial cells in the thyroid gland, and stimulates that gland to synthesize and release thyroid hormones. TSH is a glycoprotein hormone composed of two subunits which are non covalently bound to one another. The alpha subunit of TSH is also present in two other pituitary glycoprotein hormones, follicle stimulating hormone and luteinizing hormone, and, in primates, in the placental hormone chorionic gonadotropin. Each of these hormones also has a unique beta subunit, which provides receptor specificity. In other words, TSH is composed of alpha subunit bound to the TSH beta subunit, and TSH associates only with its own receptor. Free alpha and beta subunits have essentially no biological activity.Synonyms: TSH, TSH beta, TSHB, Thyroid-stimulating hormone subunit beta, Thyrotropin subunit beta
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Gene ID
- 7252
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Pathways
- Thyroid Hormone Synthesis, Peptide Hormone Metabolism
Target
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