TNK2 antibody (Middle Region)
Quick Overview for TNK2 antibody (Middle Region) (ABIN452710)
Target
See all TNK2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- Middle Region
-
Specificity
- This antibody detects TNK2 / ACK1 at Center.
-
Cross-Reactivity (Details)
- Species reactivity (tested):Human
-
Purification
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
-
Immunogen
- KLH conjugated synthetic peptide selected from the Center region of human ACK1
-
-
anti-tyrosine Kinase, Non-Receptor, 2 (TNK2) (AA 1-352) antibody
TNK2 Reactivity: Human WB, IF, IP Host: Rabbit Polyclonal unconjugated
anti-tyrosine Kinase, Non-Receptor, 2 (TNK2) (AA 10-39), (N-Term) antibodyTNK2 Reactivity: Human WB, IHC (p), FACS Host: Rabbit Polyclonal RB15601 unconjugated
anti-tyrosine Kinase, Non-Receptor, 2 (TNK2) (C-Term) antibodyTNK2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-tyrosine Kinase, Non-Receptor, 2 (TNK2) (pTyr284) antibodyTNK2 Reactivity: Human, Mouse, Rat WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-tyrosine Kinase, Non-Receptor, 2 (TNK2) (AA 21-120) antibodyTNK2 Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
anti-tyrosine Kinase, Non-Receptor, 2 (TNK2) (pTyr857), (pTyr858) antibodyTNK2 Reactivity: Human WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-tyrosine Kinase, Non-Receptor, 2 (TNK2) (AA 934-964), (C-Term) antibodyTNK2 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB3101-3102 unconjugated
anti-tyrosine Kinase, Non-Receptor, 2 (TNK2) (AA 250-299), (pTyr284) antibodyTNK2 Reactivity: Human, Mouse WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-tyrosine Kinase, Non-Receptor, 2 (TNK2) (pTyr284) antibodyTNK2 Reactivity: Human, Mouse, Rat, Cow, Pig WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-tyrosine Kinase, Non-Receptor, 2 (TNK2) (AA 1-352) antibodyTNK2 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
-
-
Application Notes
-
ELISA: 1: 1,000. Western blot: 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.25 mg/mL
-
Buffer
- PBS with 0.09 % (W/V) sodium azide
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handling Advice
- Avoid repeated freezing and thawing.
-
Storage
- 4 °C/-20 °C
-
Storage Comment
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
-
-
- TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))
-
Alternative Name
- TNK2 / ACK1
-
Background
- ACK1 is a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway.Synonyms: Activated CDC42 kinase 1
-
Molecular Weight
- 114327 Da
-
Gene ID
- 10188
-
NCBI Accession
- NP_001010938
-
UniProt
- Q07912
Target
-
