Aminomethyltransferase antibody (N-Term)

Catalog No. ABIN452734

This Rabbit Polyclonal antibody specifically detects Aminomethyltransferase in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for Aminomethyltransferase antibody (N-Term) (ABIN452734)

Target: Aminomethyltransferase (AMT)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aminomethyltransferase antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-Aminomethyltransferase Antibody

Binding Specificity: N-Term

Specificity: This antibody detects Aminomethyltransferase at N-term.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: KLH conjugated synthetic peptide selected from the N-terminal region of human AMT

Application Details

Application Notes: Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for Aminomethyltransferase

Target: Aminomethyltransferase (AMT)

Alternative Name: Aminomethyltransferase

Background: The enzyme system for cleavage of glycine (glycine cleavage system, EC 2.1.2.10), which is confined to the mitochondria, is composed of 4 protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase, MIM 238300), H protein (a lipoic acid-containing protein, MIM 238330), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase, MIM 238331). Glycine encephalopathy (GCE, MIM 605899) may be due to a defect in any one of these enzymes.Synonyms: AMT, GCST, GCVT, Glycine cleavage system T protein

Molecular Weight: 43946 Da

Gene ID: 275

NCBI Accession: NP_000472

UniProt: P48728