CBS antibody (Middle Region)

Catalog No. ABIN452820

The Rabbit Polyclonal anti-CBS antibody (ABIN452820) specifically detects CBS in WB and EIA. The antibody is reactive with Human and Mouse samples.

Quick Overview for CBS antibody (Middle Region) (ABIN452820)

Target: CBS (Cystathionine-beta-Synthase (CBS))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBS antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-CBS Antibody

Binding Specificity: Middle Region

Specificity: This antibody detects CBS at Center.

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse

Purification: Purified through a protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide selected from the Center region of human CBS

Application Details

Application Notes: Western blot: 1: 100 - 1: 500. ELISA: 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for CBS

Target: CBS (Cystathionine-beta-Synthase (CBS))

Alternative Name: CBS

Background: CBS acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. This protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria.Synonyms: Beta-thionase, Cystathionine beta-synthase, Serine sulfhydrase

Molecular Weight: 60587 Da

Gene ID: 875

NCBI Accession: NP_000062

UniProt: P35520