Ceruloplasmin antibody (Middle Region)

Catalog No. ABIN452864

The Rabbit Polyclonal anti-Ceruloplasmin antibody is suitable to detect Ceruloplasmin in samples from Human and Mouse. It has been validated for WB and EIA.

Quick Overview for Ceruloplasmin antibody (Middle Region) (ABIN452864)

Target: Ceruloplasmin (CP) (Ceruloplasmin (Ferroxidase) (CP))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ceruloplasmin antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-Ceruloplasmin Antibody

Binding Specificity: Middle Region

Specificity: This antibody detects CP at Center.

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: KLH conjugated synthetic peptide selected from the Center region of human CP

Application Details

Application Notes: Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for Ceruloplasmin

Target: Ceruloplasmin (CP) (Ceruloplasmin (Ferroxidase) (CP))

Alternative Name: Ceruloplasmin

Background: CP is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe(II)transferrin to Fe(III) transferrin. Mutations in this protein cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities.Synonyms: CP, Ferroxidase

Molecular Weight: 122205 Da

Gene ID: 1356

NCBI Accession: NP_000087

UniProt: P00450

Pathways: Transition Metal Ion Homeostasis