FGF18 antibody (N-Term)

Catalog No. ABIN452998

This Rabbit Polyclonal antibody specifically detects FGF18 in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for FGF18 antibody (N-Term) (ABIN452998)

Target: FGF18 (Fibroblast Growth Factor 18 (FGF18))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGF18 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-FGF18 Antibody

Binding Specificity: N-Term

Specificity: This antibody detects FGF18 at N-term.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: KLH conjugated synthetic peptide selected from the N-terminal region of human FGF18

Application Details

Application Notes: Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for FGF18

Target: FGF18 (Fibroblast Growth Factor 18 (FGF18))

Alternative Name: FGF18

Background: FGF18 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures.Synonyms: FGF-18, Fibroblast growth factor 18, zFGF5

Molecular Weight: 23989 Da

Gene ID: 8817

NCBI Accession: NP_003853

UniProt: O76093

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway