GLA antibody (N-Term)
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- Target See all GLA Antibodies
- GLA (Galactosidase, alpha (GLA))
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Binding Specificity
- AA 90-120, N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GLA antibody is un-conjugated
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificity
- This antibody detects GLA at N-term.
- Purification
- Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
- Immunogen
- KLH conjugated synthetic peptide between 90~120 amino acids from the N-terminal region of human GLA
- Top Product
- Discover our top product GLA Primary Antibody
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- Application Notes
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Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) sodium azide as preservative
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- Target
- GLA (Galactosidase, alpha (GLA))
- Alternative Name
- alpha-Galactosidase A (GLA Products)
- Background
- GLA is a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.Synonyms: Alpha-D-galactosidase A, Alpha-D-galactoside galactohydrolase, GLA, Melibiase
- Molecular Weight
- 48767 Da
- Gene ID
- 2717
- NCBI Accession
- NP_000160
- UniProt
- P06280
- Pathways
- SARS-CoV-2 Protein Interactome
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