GLA antibody (N-Term)

Catalog No. ABIN453055

This Rabbit Polyclonal antibody specifically detects GLA in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for GLA antibody (N-Term) (ABIN453055)

Target: GLA (Galactosidase, alpha (GLA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLA antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-GLA Antibody

Binding Specificity: AA 90-120, N-Term

Specificity: This antibody detects GLA at N-term.

Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: KLH conjugated synthetic peptide between 90~120 amino acids from the N-terminal region of human GLA

Application Details

Application Notes: Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for GLA

Target: GLA (Galactosidase, alpha (GLA))

Alternative Name: alpha-Galactosidase A

Background: GLA is a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.Synonyms: Alpha-D-galactosidase A, Alpha-D-galactoside galactohydrolase, GLA, Melibiase

Molecular Weight: 48767 Da

Gene ID: 2717

NCBI Accession: NP_000160

UniProt: P06280

Pathways: SARS-CoV-2 Protein Interactome