IMMT antibody (Middle Region)

Catalog No. ABIN453133

This Rabbit Polyclonal antibody specifically detects IMMT in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for IMMT antibody (Middle Region) (ABIN453133)

Target: IMMT (Inner Membrane Protein, Mitochondrial (IMMT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IMMT antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-IMMT Antibody

Binding Specificity: Middle Region

Specificity: This antibody reacts to Mitofilin.

Purification: Saturated Ammonium Sulfate (SAS) precipitation

Immunogen: KLH conjugated synthetic peptide selected from the Center region of human IMMT

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for IMMT

Target: IMMT (Inner Membrane Protein, Mitochondrial (IMMT))

Alternative Name: Mitofilin

Background: Mitochondria are the center of cellular energy production and essential metabolic reactions. As double membrane-bound organelles, mitochondria from different species, tissues, and metabolic states are highly polymorphic in nature, yet exhibit common structural features. The ultrastructural variations in mitochondrial architecture occur mainly due to the differences in the amount and shape of cristae. Abundant cristae are found in mitochondria from tissues where energy demand is high. Analysis of the human heart mitochondrial proteome shows that mitofilin is one of the most abundant mitochondrial proteins. It appears to play an important role in the maintenance of cristae morphology.Synonyms: Cell proliferation-inducing gene 4 protein, HMP, IMMT, Mitochondrial marker inner membrane protein, PIG4, p87/89

Gene ID: 10989

NCBI Accession: NP_001093639

UniProt: Q16891