SOD3 antibody (N-Term)
Quick Overview for SOD3 antibody (N-Term) (ABIN453388)
Target
See all SOD3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Specificity
- This antibody reacts to SOD3.
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Purification
- Saturated Ammonium Sulfate (SAS) precipitation
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Immunogen
- KLH conjugated synthetic peptide selected from the N-terminal region of human SOD3
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Application Notes
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ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- SOD3 (Superoxide Dismutase 3, Extracellular (SOD3))
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Alternative Name
- Superoxide Dismutase 3 / SOD3
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Background
- SOD3 is a member of the superoxide dismutase(SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide radicals into hydrogen peroxide and oxygen. This protein is thought to protect the brain, lungs, and other tissues from oxidative stress. The protein is secreted into the extracellular space and forms a glycosylated homotetramer that is anchored to the extracellular matrix (ECM) and cell surfaces through an interaction with heparan sulfate proteoglycan and collagen. A fraction of the protein is cleaved near the C-terminus before secretion to generate circulating tetramers that do not interact with the ECM.Synonyms: EC-SOD, Extracellular superoxide dismutase [Cu-Zn], SOD-3
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Gene ID
- 6649
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NCBI Accession
- NP_003093
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UniProt
- P08294
Target
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