VCP antibody (C-Term)

Catalog No. ABIN453454

This Rabbit Polyclonal antibody specifically detects VCP in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for VCP antibody (C-Term) (ABIN453454)

Target: VCP (Valosin Containing Protein (VCP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VCP antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-VCP Antibody

Binding Specificity: C-Term

Specificity: This antibody reacts to TER ATPase.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide selected from the C-terminal region of human VCP

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for VCP

Target: VCP (Valosin Containing Protein (VCP))

Alternative Name: TER ATPase / VCP

Background: VCP is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. This protein, as a structural protein, is associated with clathrin, and heat-shock protein Hsc70, to form a complex. It has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation.Synonyms: 15S Mg(2+)-ATPase p97 subunit, Transitional endoplasmic reticulum ATPase, Valosin-containing protein

Gene ID: 7415

NCBI Accession: NP_009057

UniProt: P55072

Pathways: ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Ubiquitin Proteasome Pathway