Sorbs2 antibody (N-Term)

Catalog No. ABIN453519

The Rabbit Polyclonal anti-Sorbs2 antibody (ABIN453519) specifically detects Sorbs2 in WB and EIA. The antibody is reactive with Human samples.

Quick Overview for Sorbs2 antibody (N-Term) (ABIN453519)

Target: Sorbs2 (Sorbin and SH3 Domain Containing 2 (Sorbs2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Sorbs2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-Sorbs2 Antibody

Binding Specificity: N-Term

Specificity: This antibody reacts to ARGBP2.

Purification: Saturated Ammonium Sulfate (SAS) precipitation

Immunogen: KLH conjugated synthetic peptide selected from the N-terminal region of human ARGBP2

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Sorbs2

Target: Sorbs2 (Sorbin and SH3 Domain Containing 2 (Sorbs2))

Alternative Name: SORBS2 / Sorbin

Background: Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. ARGBP2 is the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology(SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton.Synonyms: ARGBP2, KIAA0777, Sorbin and SH3 domain-containing protein 2

Gene ID: 8470

NCBI Accession: NP_003594

UniProt: O94875