RBBP7 antibody (N-Term)

Catalog No. ABIN453808

This Rabbit Polyclonal antibody specifically detects RBBP7 in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for RBBP7 antibody (N-Term) (ABIN453808)

Target: RBBP7 (Retinoblastoma Binding Protein 7 (RBBP7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBBP7 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-RBBP7 Antibody

Binding Specificity: N-Term

Specificity: This antibody reacts to RBBP7.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide selected from the N-terminal region of human RBBP7

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for RBBP7

Target: RBBP7 (Retinoblastoma Binding Protein 7 (RBBP7))

Alternative Name: RBBP7 / RBAP46

Background: RBBP7 is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. This protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation.Synonyms: Histone-binding protein RBBP7, Nucleosome-remodeling factor subunit RBAP46, RBBP-7, Retinoblastoma-binding protein 7, Retinoblastoma-binding protein p46

Gene ID: 5931

NCBI Accession: NP_002884

UniProt: Q16576