DcR1 antibody (FITC)
Quick Overview for DcR1 antibody (FITC) (ABIN457355)
Target
See all DcR1 (TNFRSF10C) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- Anti-Hu CD263 FITC
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Cross-Reactivity (Details)
- Human
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Characteristics
- The antibody TRAIL-R3-02 reacts with TRAIL-R3, a 35 kDa GPI-anchored extracellular membrane protein expressed mainly on neutrophils.
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Purification
- Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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Immunogen
- TRAIL-R3-hIgGhc fusion protein
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Isotype
- IgG1
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anti-Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C) antibody
TNFRSF10C Reactivity: Human FACS Host: Mouse Monoclonal TRAIL-R3-02 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C) antibodyTNFRSF10C Reactivity: Human, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C) (AA 26-236) antibodyTNFRSF10C Reactivity: Human ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C) (AA 30-130) antibodyTNFRSF10C Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C) antibodyTNFRSF10C Reactivity: Human WB, FACS Host: Rabbit Monoclonal 24GB2005 unconjugated Recombinant Antibody
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C) antibody (APC)TNFRSF10C Reactivity: Human FACS Host: Mouse Monoclonal TRAIL-R3-02 APC
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C) antibodyTNFRSF10C Reactivity: Human FACS, IHC Host: Mouse Monoclonal TR3-06 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C) antibody (PE)TNFRSF10C Reactivity: Human FACS Host: Mouse Monoclonal TRAIL-R3-02 PE
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C) (Internal Region) antibodyTNFRSF10C Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
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Application Notes
- Flow cytometry: Recommended dilution: 1-5 μg/mL.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.1 mg/mL
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Buffer
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Do not freeze,Protect from prolonged exposure to light
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Storage
- 4 °C
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Storage Comment
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))
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Alternative Name
- CD263
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Background
- TNF receptor superfamily member 10c,TRAIL-R3 (CD263, TR3, DcR1, LIT, TRID), expressed mainly on neutrophils, belongs to receptors of TRAIL, a TNF-like membrane cytotoxic protein that induces apoptosis in many tumour cells, but not in normal cells. TRAIL-R3, however, is a GPI-anchored protein that lacks cytoplasmic death domain, thus it is unable to induce apoptosis and serves as a negative regulator of apoptotic signaling by competing for binding of TRAIL with death receptor 5 (DR5).,TNFRSF10C, DcR1, TRAIL-R3, TRID, LIT
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Gene ID
- 8794
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UniProt
- O14798
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Pathways
- Apoptosis
Target
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