PARP1 antibody (AA 151-385)

Catalog No. ABIN467410

This Rabbit Polyclonal antibody specifically detects PARP1 in WB, IF and ICC. It exhibits reactivity toward Human.

Quick Overview for PARP1 antibody (AA 151-385) (ABIN467410)

Target: PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PARP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-PARP1 Antibody

Binding Specificity: AA 151-385

Specificity: Human PARP1. Predicted cross-reactivity based on amino acid sequence homology: mouse (86 % ), rat (85 %), bovine (89 %).

Purification: Immunoaffinity purified

Immunogen: Recombinant protein fragment containing a sequence corresponding to a region within amino acids 151 and 385 of PARP1.

Type of Immunogen: Recombinant protein

Application Details

Application Notes: Approved: ICC, IF (1:100 - 1:200), WB (1:500 - 1:3000)

Not recommended for: IHC-P

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7, 40 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C. Avoid freeze-thaw cycles.

Target Details for PARP1

Target: PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Alternative Name: PARP1 / PARP

Background: Name/Gene ID: PARP1

Synonyms: PARP1, ADPRT, ADP-ribosyltransferase NAD(+), Adp-ribosyltransferase, ADPRT1, ARTD1, ADPRT 1, Poly(ADP-ribose) synthetase, Poly(ADP-ribosyl)transferase, PARP, Poly [ADP-ribose] polymerase 1, PADPRT-1, PARP-1, Poly (ADP-ribose) polymerase 1, Poly(ADP-ribose) polymerase, Poly[ADP-ribose] synthase 1, PPOL

Gene ID: 142

UniProt: P09874

Pathways: Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location