GPR158 antibody (AA 1-50)

Catalog No. ABIN486340

This Rabbit Polyclonal antibody specifically detects GPR158 in WB, ELISA, IHC and IF. It exhibits reactivity toward Human and Mouse. It has been mentioned in 2+ publications

Quick Overview for GPR158 antibody (AA 1-50) (ABIN486340)

Target: GPR158 (G Protein-Coupled Receptor 158 (GPR158))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR158 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-GPR158 Antibody

Binding Specificity: AA 1-50

Purpose: GPR158 Antibody

Specificity: GPR158 Polyclonal Antibody detects endogenous levels of GPR158 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human GPR158. AA range:1-50

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

References for anti-GPR158 antibody (ABIN486340)

Asthana, Li, Lu, Wu, Zhang, Li, Wong, Gurung, Zhang, Lin, Peng, Xu, Chan, Zhai, Lyu, Bian, Ge, Iyaswamy, Li, Su, Zhou, Xu, Wong: "MT1-MMP inhibition rejuvenates ageing brain and rescues cognitive deficits in obesity." in: Cell discovery, Vol. 11, Issue 1, pp. 76, (2025) (PubMed).

Khrimian, Obri, Ramos-Brossier, Rousseaud, Moriceau, Nicot, Mera, Kosmidis, Karnavas, Saudou, Gao, Oury, Kandel, Karsenty: "Gpr158 mediates osteocalcin's regulation of cognition." in: The Journal of experimental medicine, Vol. 214, Issue 10, pp. 2859-2873, (2017) (PubMed).

Target Details for GPR158

Target: GPR158 (G Protein-Coupled Receptor 158 (GPR158))

Alternative Name: GPR158

Background:

Synonyms: GPR158, KIAA1136, Probable G-protein coupled receptor 158

Background: function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 3 family.,

Gene Name: GPR158

Protein Name: Probable G-protein coupled receptor 158

Molecular Weight: 135 kDa

Gene ID: 57512

UniProt: Q5T848

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling