Cortisone antibody

Catalog No. ABIN487622

Product Details anti-Cortisone Antibody

Target: Cortisone (COR)

Reactivity: Please inquire

Host: Sheep

Clonality: Polyclonal

Conjugate: This Cortisone antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Purification: Ig Fraction

Immunogen: Cortisone-BTG

Isotype: IgG

Application Details

Application Notes: ELISA: 1.25 μg/mL, 10 ng/mL cortisone produces 73 % inhibition in a competitive ELISA,employing cortisone polyclonal antibody.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 7.2mg/mL (U.V.abs at 280nm)

Buffer: 20 mM Phosphate, 150 mM Sodium Chloride, pH 7.2 containing 0.09 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for Cortisone

Target: Cortisone (COR)

Alternative Name: Cortisone (COR Products)

Target Type: Hormone

Background: Cortisone is a hormone. Chemically it is a corticosteroid with formula C21H28O5 and IUPAC name 17-hydroxy-11-dehydrocorticosterone. It is closely related to corticosterone. Cortisone and adrenaline are the main hormones released by the body as a reaction to stress. They elevate blood pressure and prepare the body for a fight or flight response. Cortisone is the inactive precursor molecule of the active hormone cortisol. It is activated through hydroxylation of the 11-keto-group by an enzyme called 11-beta-steroid dehydrogenase. The active form cortisol is thus sometimes referred to as hydrocortisone. Cortisone is sometimes used as a drug to treat a variety of ailments.Synonyms: 11, 17alpha, 17alpha-Hydroxy-11-dehydrocorticosterone, 20-trione, 21-Dihydroxy-4-pregnene-3, 21-diol-3, 4-Pregnene-17alpha