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Imipramine antibody

EIA Host: Sheep Polyclonal unconjugated
Catalog No. ABIN487706
  • Target See all Imipramine products
    Imipramine
    Host
    • 2
    • 2
    Sheep
    Clonality
    • 2
    • 2
    Polyclonal
    Conjugate
    • 4
    This Imipramine antibody is un-conjugated
    Application
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Enzyme Immunoassay (EIA)
    Purification
    Ig Fraction
    Immunogen
    Imipramine-BTG
    Isotype
    IgG
  • Application Notes
    ELISA: 0.625 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    6.38 mg/mL (U.V.abs at 280nm)
    Buffer
    20 mM Phosphate, 150 mM Sodium Chloride, pH 7.2 containing 0.09 % Sodium Azide as preservative.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store the antibody (in aliquots) at-20 °C.
  • Target
    Imipramine
    Abstract
    Imipramine Products
    Target Type
    Chemical
    Background
    Tricyclic antidepressants contain a characteristic three ringed nucleus structure. They act primarily as serotoninnorepinephrine reuptake inhibitors. Tricyclic antidepressants are mainly used as antidepressants, but have also been for the treatment of anxiety disorders and attention hyperactivity disorder and as an adjunct to certain analgesics to treat chronic pain. In many treatments they have been replaced by other compounds with fewer sideeffects. Tricyclic antidepressants are not considered addictive and have a low abuse potential, but suddenly discontinuing treatment may results in discontinuation syndrome and overdose is a main cause of death from prescription drugs. They have significant cardiovascular and neurological toxicity. Monitoring of TCA levels can help determine toxicity, monitor compliance and establish individual target concentrations. Imipramine is a member of the family of tricyclic antidepressants. Its clinical effect is hypothesized as being due to potentiation of adrenergic synapses by blocking uptake of norepinephrine at nerve endings. Imipramine is a very powerful antidepressant and is converted to desipramine in the body.Synonyms: Antideprin, Berkomine, Cristalia, Melipramine, Prazepine, Sermonil, Tricyclic Antidepressant
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