Morphine-3 antibody
Quick Overview for Morphine-3 antibody (ABIN487780)
Target
Host
Clonality
Conjugate
Application
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Purification
- Ig Fraction
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Immunogen
- Morphine (3)-BSA
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Isotype
- IgG
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Application Notes
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ELISA: 1.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 6.55mg/mL (U.V. abs at 280nm)
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Buffer
- 20 mM Phosphate, 150 mM Sodium Chloride, pH 7.2 containing 0.09 % Sodium Azide as preservative
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- -20 °C
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- Morphine-3
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Target Type
- Chemical
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Background
- Morphine is thought to produce reinforcement phenomena via stimulation of mu, delta, and kappa opioid receptors that regulate stress perception, pain control, reward behavior, and neurohormone secretion in reward-relevant brain systems. It has the highest affinity for mu, followed by delta and kappa. Rapid activation of the mu opioid receptor by morphine results in a euphoric phenotype, thus conferring the reinforcing effects of the drug. This activation is accompanied by extracellular dopamine release, which alters several events related to the cAMP signal transduction pathway. Of particular significance is that CREB seems to be modified by morphine, thereby affecting addictive behavioral phenomena, such as withdrawal symptoms.Synonyms: (5a, 3 Carboxymethyl Morphine, 4, 5-epoxy-17-methylmorphinan-3, 6-diol, 6a)-7, 8-didehydro-
Target
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