CYBB antibody (HRP)
Quick Overview for CYBB antibody (HRP) (ABIN4880112)
Target
See all CYBB AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- This antibody recognises Cytochrome b-245 heavy chain (CYBB), which is also know as NOX2/gp91phox. NOX2/gp91phox is a component of the membrane-bound oxidase of phagocytes that generates superoxide. Defects in the CYBB gene are a cause of Chronic X-linked granulomatous disease (CGD). This antibody is specific for NOX2/gp91phox 382-PKIAVDGP-389
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Purification
- Protein G purified
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Immunogen
- Partially Purified human neutrophil flavocytochrome b (heparin Ultrogellectin affinity purification in Triton X-100)
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Isotype
- IgG1
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Application Notes
- Optimal antibody dilution should be determined by titration.
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Comment
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Myeloma, fusion partnersSP2/0
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Purified IgG conjugated to Horseradish Peroxidase using Innova Biosciences Lightning-Link ®, supplied in Phosphate buffered saline (PBS) containing 0.01 % Thiomersal
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Preservative
- Thimerosal (Merthiolate)
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Precaution of Use
- This product contains Thimerosal (Merthiolate) a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- CYBB (Cytochrome B-245, beta Polypeptide (CYBB))
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Alternative Name
- NOX2/gp91phox
Target
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