CYBB antibody (AA 283-570)

Catalog No. ABIN7149094

Product Details anti-CYBB Antibody

Target: CYBB (Cytochrome B-245, beta Polypeptide (CYBB))

Binding Specificity: AA 283-570

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYBB antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Cytochrome b-245 heavy chain protein (283-570AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CYBB

Target: CYBB (Cytochrome B-245, beta Polypeptide (CYBB))

Alternative Name: CYBB (CYBB Products)

Synonyms: zgc:64144 antibody, cgd antibody, gp91-1 antibody, gp91-phox antibody, gp91phox antibody, nox2 antibody, NOX2 antibody, cybb antibody, NOX1 antibody, AMCBX2 antibody, CGD antibody, GP91-1 antibody, GP91-PHOX antibody, GP91PHOX antibody, p91-PHOX antibody, Nox2 antibody, C88302 antibody, CGD91-phox antibody, Cgd antibody, Cyd antibody, Gp91-phox antibody, CYBB antibody, cytochrome b-245, beta polypeptide (chronic granulomatous disease) antibody, cytochrome b-245, beta polypeptide antibody, cytochrome b-245 heavy chain antibody, cytochrome b-245, beta polypeptide L homeolog antibody, cytochrome b-245 beta polypeptide antibody, cytochrome b-245 beta chain antibody, NADPH oxidase heavy chain subunit antibody, cybb antibody, CYBB antibody, cybb.L antibody, Cybb antibody, GP91-PHOX antibody

Background:

Background: Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H+ currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc.

Aliases: AMCBX2 antibody, CGD antibody, CGD91-phox antibody, CY24B_HUMAN antibody, CYBB antibody, Cytochrome b 245, beta polypeptide antibody, Cytochrome b(558) beta chain antibody, Cytochrome b(558) subunit beta antibody, Cytochrome b-245 heavy chain antibody, Cytochrome b558 subunit beta antibody, GP91 PHOX antibody, gp91-1 antibody, gp91-phox antibody, GP91PHOX antibody, Heme-binding membrane glycoprotein gp91phox antibody, NADPH oxidase 2 antibody, Neutrophil cytochrome b 91 kDa polypeptide antibody, NOX2 antibody, p22 phagocyte B-cytochrome antibody, P91 PHOX antibody, p91-PHOX antibody, Superoxide-generating NADPH oxidase heavy chain subunit antibody

UniProt: P04839