Flotillin 2 antibody (C-Term)

Catalog No. ABIN488109

The Rabbit Polyclonal anti-Flotillin 2 antibody (ABIN488109) specifically detects Flotillin 2 in WB, IF and IHC (p). The antibody is reactive with Human samples.

Quick Overview for Flotillin 2 antibody (C-Term) (ABIN488109)

Target: Flotillin 2 (FLOT2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Flotillin 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Flotillin 2 Antibody

Binding Specificity: C-Term

Specificity: Recognizes Flotillin-2/FLOT2.
Cellular Localization: Cell membrane, Peripheral membrane protein, Membrane, caveola, Peripheral membrane protein.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Antigen-Affinity Chromatography.

Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 365 and 378 of Flotillin-2

Application Details

Application Notes: Western blot: 1/500-1/3000Immunofluorescence: 1/100-1/200. Immunohistochemistry with Formalin-Fixed Paraffin-Embedded Sections : 1/100-1/250. Positive Controls: HeLaS3.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: 1xPBS, 1 % BSA, 20 % Glycerol ( pH 7) containing 0.01 % Thimerosal as preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody undiluted at (in aliquots) at -20 °C.

Target Details for Flotillin 2

Target: Flotillin 2 (FLOT2)

Alternative Name: Flotillin-2 / FLOT2

Background: Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. Flotillin 2 may act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function.Synonyms: ESA, ESA1, Epidermal surface antigen, M17S1, REG-1, Reg1, Reggie-1

Molecular Weight: 47 kDa

Gene ID: 2319

NCBI Accession: NP_004466

UniProt: Q14254