EPH Receptor A2 antibody
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- Target See all EPH Receptor A2 (EPHA2) Antibodies
- EPH Receptor A2 (EPHA2)
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This EPH Receptor A2 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- Specificity
- Recognizes EphA2 receptor tyrosine kinase (EphA2).
- Cross-Reactivity (Details)
- Species reactivity (tested):Human.
- Purification
- Affinity Chromatography on Protein G.
- Immunogen
- Genetic immunisation with cDNA encoding Human EphA2 Remarks: Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells
- Clone
- GM5H5
- Isotype
- IgG1
- Top Product
- Discover our top product EPHA2 Primary Antibody
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anti-EPH Receptor A2 (EPHA2) (AA 30-60), (N-Term) antibody
EPHA2 Reactivity: Human, Mouse WB, FACS, IHC (p) Host: Rabbit Polyclonal RB01579 unconjugated
anti-EPH Receptor A2 (EPHA2) (AA 901-976) antibodyEPHA2 Reactivity: Human, Mouse, Rat WB, ELISA, IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-EPH Receptor A2 (EPHA2) (AA 204-326) antibodyEPHA2 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 1E3 unconjugated
anti-EPH Receptor A2 (EPHA2) antibodyEPHA2 Reactivity: Human FACS, IF, cELISA Host: Mouse Monoclonal Kalpha-5H5 unconjugated
anti-EPH Receptor A2 (EPHA2) (AA 30-60) antibodyEPHA2 Reactivity: Human, Mouse WB, ELISA, IHC, FACS Host: Rabbit Polyclonal unconjugated
anti-EPH Receptor A2 (EPHA2) (AA 333-347), (Extracellular), (N-Term) antibodyEPHA2 Reactivity: Human, Mouse, Rat WB, IHC, FACS Host: Rabbit Polyclonal unconjugated
anti-EPH Receptor A2 (EPHA2) antibodyEPHA2 Reactivity: Human WB, ELISA, IHC Host: Mouse Monoclonal 1B3C7 unconjugated
anti-EPH Receptor A2 (EPHA2) (AA 847-976) antibodyEPHA2 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-EPH Receptor A2 (EPHA2) (AA 627-976) antibodyEPHA2 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-EPH Receptor A2 (EPHA2) (pTyr594) antibodyEPHA2 Reactivity: Human WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) Host: Rabbit Polyclonal unconjugated
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- Application Notes
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cELISA: 1/200-1/400. Flow Cytometry: 1.2 μg/10^6 cells. Immunofluorescence: 1 μg/10^6 cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 2.0 mg/mL
- Buffer
- Phosphate buffered saline, pH 7.2
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- EPH Receptor A2 (EPHA2)
- Alternative Name
- EPHA2 / ECK (EPHA2 Products)
- Background
- EphA2 (Eph receptor tyrosine kinase A2) belongs to the Eph tyrosine receptor familiy, the largest receptor tyrosine kinase family of transmembrane proteins. It encodes a 130 kDA transmembrane protein which is primarily found in adult human epithelial cells (1). Eph receptors and their ephrin ligands are important mediators of cell-cell communication and play roles in embryonic patterning, neuronal targeting, and vascular development during normal embryogenesis (2,3). The Eph family of receptor tyrosine kinases is frequently overexpressed in a wide variety of cancers and tumor cell lines. In particular, EphA2 is overexpressed in prostate, lung and colon cancers and 40 % of breast cancers and it represent an attractive potential target for drug design (3,4).Synonyms: Eph receptor A2, Ephrin type-A receptor 2, Epithelial cell kinase, Tyrosine-protein kinase receptor ECK
- Gene ID
- 1969
- NCBI Accession
- NP_004422
- UniProt
- P29317
- Pathways
- RTK Signaling
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