ADH5 antibody (AA 212-374)

Catalog No. ABIN4886429

Product Details anti-ADH5 Antibody

Target: ADH5 (Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5))

Binding Specificity: AA 212-374

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADH5 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Alcohol dehydrogenase class-3(ADH5) detection. Tested with WB in Human,Mouse,Rat.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Alcohol dehydrogenase class-3(ADH5) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: alcohol dehydrogenase 5 (class III), chi polypeptide
Protein Name: Alcohol dehydrogenase class-3

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human ADH5 recombinant protein (Position: K212-I374). Human ADH5 shares 90.2% and 92% amino acid (aa) sequence identity with mouse and rat ADH5, respectively.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for ADH5

Target: ADH5 (Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5))

Alternative Name: ADH5 (ADH5 Products)

Synonyms: ADH2 antibody, ADH-3 antibody, ADHX antibody, FALDH antibody, FDH antibody, GSH-FDH antibody, GSNOR antibody, ADH1C antibody, ADH3 antibody, wu:fb60b11 antibody, Adh-5 antibody, Adh3 antibody, adh-3 antibody, adh3 antibody, adh5 antibody, adhx antibody, fdh antibody, gsnor antibody, ADH4 antibody, ADH5 antibody, alcohol dehydrogenase 1B (class I), beta polypeptide antibody, alcohol dehydrogenase 5 (class III), chi polypeptide antibody, alcohol dehydrogenase 5 antibody, alcohol dehydrogenase 5 (class III), chi polypeptide L homeolog antibody, alcohol dehydrogenase class-3 antibody, ADH1B antibody, ADH5 antibody, adh5 antibody, Adh5 antibody, adh5.L antibody, LOC101112223 antibody

Background: Alcohol dehydrogenase class-3 is an enzyme that in humans is encoded by the ADH5 gene. This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene.

Synonyms: ADH 3 | ADH5 | ADHX | FALDH | FDH | formaldehyde dehydrogenase | GSH-FDH | GSNOR | P11766

Gene ID: 128

UniProt: P11766