FSHR antibody (AA 18-187)

Catalog No. ABIN4886595

Product Details anti-FSHR Antibody

Target: FSHR (Follicle Stimulating Hormone Receptor (FSHR))

Binding Specificity: AA 18-187

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FSHR antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Follicle-stimulating hormone receptor(FSH-R)(FSHR) detection. Tested with WB in Human,Mouse,Rat.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Follicle-stimulating hormone receptor(FSH-R)(FSHR) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: follicle stimulating hormone receptor
Protein Name: Follicle-stimulating hormone receptor(FSH-R)

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human FSH Receptor recombinant protein (Position: C18-N187). Human FSH Receptor shares 91.2% and 90% amino acid (aa) sequence identity with mouse and rat FSH Receptor, respectively.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

References for anti-FSHR antibody (ABIN4886595)

Wu, Shi, Gong, Yu, Chen, Wang, Sun: "Evaluation of follicular synchronization caused by estrogen administration and its reproductive outcome." in: PLoS ONE, Vol. 10, Issue 5, pp. e0127595, (2016) (PubMed).

Target Details for FSHR

Target: FSHR (Follicle Stimulating Hormone Receptor (FSHR))

Alternative Name: FSHR (FSHR Products)

Synonyms: FSHRO antibody, LGR1 antibody, ODG1 antibody, FSH-R antibody, eFSHR antibody, FSHRE antibody, fshr antibody, FSHR antibody, fshr-A antibody, GTHR-I antibody, zfGTHR-I antibody, LOC100304505 antibody, follicle stimulating hormone receptor antibody, follicle stimulating hormone receptor L homeolog antibody, follicle-stimulating hormone receptor antibody, FSHR antibody, fshr antibody, Fshr antibody, fshr.L antibody, Bm1_17785 antibody, LOC100304505 antibody

Background: The follicle-stimulating hormone receptor or FSH receptor (FSHR) is a transmembrane receptor that interacts with the follicle-stimulating hormone (FSH) and represents a G protein-coupled receptor (GPCR). This FSHR gene is mapped to chromosome 2p21 by fluorescence in situ hybridization. The protein encoded by this gene belongs to family 1 of G-protein coupled receptors. It is the receptor for follicle stimulating hormone and functions in gonad development. Mutations in this gene cause ovarian dysgenesis type 1, and also ovarian hyperstimulation syndrome. Alternative splicing results in multiple transcript variants.

Synonyms: Follitropin receptor | FSH Receptor | FSHR | FSH-R | FSHReceptor | LGR1 | ODG1 | P23945

Gene ID: 2492

UniProt: P23945

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Platelet-derived growth Factor Receptor Signaling