LRIG3 antibody (Middle Region)

Catalog No. ABIN4886661

The Rabbit Polyclonal anti-LRIG3 antibody (ABIN4886661) specifically detects LRIG3 in WB. The antibody is reactive with Human and Rat samples.

Quick Overview for LRIG3 antibody (Middle Region) (ABIN4886661)

Target: LRIG3 (Leucine-Rich Repeats and Immunoglobulin-Like Domains 3 (LRIG3))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRIG3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LRIG3 Antibody

Binding Specificity: Middle Region

Purpose: Anti-LRIG3 Antibody

Sequence: NAFSQMKKLQ QLHLNTSSLL CDCQLKWLPQ WVAENNFQ

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: different from the related mouse sequence by one amino acid.

Characteristics: Anti-LRIG3 Antibody. Tested in WB applications. This antibody reacts with Human, Rat.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human LRIG3, different from the related mouse sequence by one amino acid.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human, Rat

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for LRIG3

Target: LRIG3 (Leucine-Rich Repeats and Immunoglobulin-Like Domains 3 (LRIG3))

Alternative Name: LRIG3

Background:

Background: LRIG3 (leucine-rich repeats and Ig-like domains-3) is a 140 kDa type I transmembrane glycoprotein member of the mammalian LRIG glycoprotein family. It shares 46.8 % and 54.0 % amino acid identity with LRIG1 and LRIG2, respectively, with highest conservation in the extracellular, transmembrane, and membrane-proximal sequences. This gene is mapped to chromosome 12q13.2. LRIG3 may play a role in craniofacial and inner ear morphogenesis during embryonic development. It also may act within the otic vesicle epithelium to control formation of the lateral semicircular canal in the inner ear, possibly by restricting the expression of NTN1.

Gene Full Name: leucine rich repeats and immunoglobulin like domains 3

Molecular Weight: 123 kDa

Gene ID: 121227

UniProt: Q6UXM1