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TLN2 antibody (Middle Region)

TLN2 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN4886745
  • Target See all TLN2 Antibodies
    TLN2 (Talin 2 (TLN2))
    Binding Specificity
    • 5
    • 1
    • 1
    • 1
    • 1
    AA 1787-1822, Middle Region
    Reactivity
    Human, Mouse, Rat
    Host
    • 17
    • 2
    • 1
    Rabbit
    Clonality
    • 17
    • 3
    Polyclonal
    Conjugate
    • 8
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TLN2 antibody is un-conjugated
    Application
    • 10
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purpose
    Rabbit IgG polyclonal antibody for Talin-2(TLN2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Sequence
    NPKAQHTHDA ITEAAQLMKE AVDDIMVTLN EAASEV
    Cross-Reactivity (Details)
    No cross reactivity with other proteins.
    Characteristics
    Rabbit IgG polyclonal antibody for Talin-2(TLN2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: talin 2
    Protein Name: Talin-2
    Purification
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence in the middle region of human Talin 2 (1787-1822aa NPKAQHTHDAITEAAQLMKEAVDDIMVTLNEAASEV).
    Isotype
    IgG
    Top Product
    Discover our top product TLN2 Primary Antibody
  • Application Notes
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Comment

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Li, Li, Qi, Rychahou, Jafari, Huang: "The role of talin2 in breast cancer tumorigenesis and metastasis." in: Oncotarget, Vol. 8, Issue 63, pp. 106876-106887, (2017) (PubMed).

  • Target
    TLN2 (Talin 2 (TLN2))
    Alternative Name
    TLN2 (TLN2 Products)
    Synonyms
    TLN2 antibody, ilweq antibody, talin-2 antibody, ILWEQ antibody, 5730421P04Rik antibody, AI507121 antibody, AI787438 antibody, AL118320 antibody, mKIAA0320 antibody, RGD1565416 antibody, talin 2 antibody, talin 2 S homeolog antibody, TLN2 antibody, tln2.S antibody, tln2 antibody, Tln2 antibody
    Background
    Talin 2 is a protein in humans that is encoded by the TLN2 gene. It belongs to the talin protein family. This gene encodes a protein related to talin 1, a cytoskeletal protein that plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. Talin-2 is expressed at high levels in cardiac muscle and functions to provide linkages between the extracellular matrix and actin cytoskeleton at costamere structures to transduce force laterally.

    Synonyms: Talin2 | Talin 2 | Talin-2 | TLN2 | TLN 2 | TLN-2 | ILWEQ | Q9Y4G6
    Gene ID
    83660
    UniProt
    Q9Y4G6
    Pathways
    Cell-Cell Junction Organization, Maintenance of Protein Location
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