PLAUR antibody

Catalog No. ABIN4888507

The Mouse Monoclonal anti-PLAUR antibody is suitable to detect PLAUR in samples from Human. It has been validated for FACS.

Quick Overview for PLAUR antibody (ABIN4888507)

Target: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PLAUR antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: VIM5

Product Details anti-PLAUR Antibody

Purpose: Anti-Hu CD87 Purified

Cross-Reactivity (Details): Human

Characteristics: The mouse monoclonal antibody VIM5 recognizes CD87 (urokinase plasminogen activator receptor), a 36-68 kDa single-chain GPI-anchored extracellular glycoprotein expressed on granulocytes, monocytes/macrophages, dendritic cells, endothelial cells, fibroblasts and keratinocytes.

Purification: Purified by protein-A affinity chromatography.

Purity: > 95 % (by SDS-PAGE)

Immunogen: human myeloid cell line THP-1

Isotype: IgG1

Application Details

Application Notes: Flow cytometry: Recommended dilution: 1-4 μg/mL

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for PLAUR

Target: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Alternative Name: CD87

Background: Plasminogen activator, urokinase receptor,CD87, the urokinase plasminogen activator receptor (UPAR), is a GPI-anchored single chain glycoprotein of a 50-68 kDa, which is expressed on granulocytes, monocytes/macrophages, dendritic cells, endothelial cells, fibroblasts and keratinocytes. The urokinase plasminogen activator bound to CD87 converts plasminogen to plasmin, and being concentrated on the leading edge of migrating cells, it plays important role in cell adhesion and chemotaxis. CD87 binds to β,1, β,2, and β,3 integrins, and can contribute to cancer cell invasion and metastasis. This antigen can also be used to study normal and abnormal granulopoiesis.,UPAR, URKR, PLAUR

Gene ID: 5329

UniProt: Q03405

Pathways: Inositol Metabolic Process