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Neutralization (Neut)rophil Elastase antibody

This Mouse Monoclonal antibody specifically detects Neutralization (Neut)rophil Elastase in ELISA and Neut. It exhibits reactivity toward Human.
Catalog No. ABIN4888559
$277.96
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Quick Overview for Neutralization (Neut)rophil Elastase antibody (ABIN4888559)

Target

Neutralization (Neut)rophil Elastase

Reactivity

Human

Host

  • 2
Mouse

Clonality

  • 2
Monoclonal

Conjugate

  • 2
Un-conjugated

Application

ELISA, Neutralization (Neut)

Clone

ELA10-103-2
  • Purpose

    Anti-Elastase (Neutrophil) Mouse Monoclonal Antibody

    Cross-Reactivity

    Human

    Immunogen

    Purified human neutrophil elastase.

    Isotype

    IgG2b
  • Application Notes

    These antibodies have been qualified for use in ELISA to detect human neutrophil elastase and in studies of inhibition and enzyme kinetics of human neutrophil elastase.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Reconstitution

    Dilute in PBS or medium that is identical to that used in the assay system.

    Concentration

    Lot specific

    Buffer

    PBS, pH 7.4

    Storage

    -20 °C,-80 °C

    Storage Comment

    These antibodies are stable for at least one (1) year at -20°C to -70°C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.
  • Target

    Neutralization (Neut)rophil Elastase

    Background

    Neutrophil elastase,Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis (PubMed:15140022). Capable of killing E.coli but not S.aureus in vitro, digests outer membrane protein A (ompA) in E.coli and K.pneumoniae (PubMed:10947984). {PubMed:10947984, PubMed:15140022}.,Cytoplasmic vesicle, phagosome,EC 3.4.21.37, Bone marrow serine protease, Elastase-2, Human leukocyte elastase, HLE, Medullasin, PMN elastase

    UniProt

    P08246
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