Neutralization (Neut)rophil Elastase antibody
Quick Overview for Neutralization (Neut)rophil Elastase antibody (ABIN4888559)
Target
Reactivity
Host
Clonality
Conjugate
Application
Clone
-
-
Purpose
- Anti-Elastase (Neutrophil) Mouse Monoclonal Antibody
-
Cross-Reactivity
- Human
-
Immunogen
- Purified human neutrophil elastase.
-
Isotype
- IgG2b
-
-
-
-
Application Notes
- These antibodies have been qualified for use in ELISA to detect human neutrophil elastase and in studies of inhibition and enzyme kinetics of human neutrophil elastase.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Reconstitution
- Dilute in PBS or medium that is identical to that used in the assay system.
-
Concentration
- Lot specific
-
Buffer
- PBS, pH 7.4
-
Storage
- -20 °C,-80 °C
-
Storage Comment
- These antibodies are stable for at least one (1) year at -20°C to -70°C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.
-
-
- Neutralization (Neut)rophil Elastase
-
Background
- Neutrophil elastase,Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis (PubMed:15140022). Capable of killing E.coli but not S.aureus in vitro, digests outer membrane protein A (ompA) in E.coli and K.pneumoniae (PubMed:10947984). {PubMed:10947984, PubMed:15140022}.,Cytoplasmic vesicle, phagosome,EC 3.4.21.37, Bone marrow serine protease, Elastase-2, Human leukocyte elastase, HLE, Medullasin, PMN elastase
-
UniProt
- P08246
Target
-