KCNJ3 antibody (C-Term)

Catalog No. ABIN4889148

This anti-KCNJ3 antibody is a Rabbit Polyclonal antibody detecting KCNJ3 in WB, IF and ELISA. Suitable for Human.

Quick Overview for KCNJ3 antibody (C-Term) (ABIN4889148)

Target: KCNJ3 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 (KCNJ3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNJ3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA

Product Details anti-KCNJ3 Antibody

Binding Specificity: C-Term

Specificity: Reacts with human 56 kDa GIRK-1 protein

Cross-Reactivity: Mouse (Murine), Rat (Rattus)

Cross-Reactivity (Details): Cross reacts with protein from mouse, rat and other species due to sequence homology.

Purification: Purified (protein A)

Immunogen: Synthetic peptide derived from Cter domain of GIRK-1 protein

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
IF1:200 - 1:1000 WB1:500 - 1:5000

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Concentration: 1 mg/mL

Buffer: Tris 0,1M, glycine 0,1M, sucrose 2 %

Storage: 4 °C/-20 °C

Storage Comment: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 24 months

Target Details for KCNJ3

Target: KCNJ3 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 (KCNJ3))

Alternative Name: G Protein-Activated Inward Rectifier Potassium Channel 1 (GIRK-1)

Background: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

Gene ID: 3760

UniProt: P48549