KCNJ3 antibody (AA 350-487)

Catalog No. ABIN7153285

Product Details anti-KCNJ3 Antibody

Target: KCNJ3 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 (KCNJ3))

Binding Specificity: AA 350-487

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNJ3 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human G protein-activated inward rectifier potassium channel 1 protein (350-487AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for KCNJ3

Target: KCNJ3 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 (KCNJ3))

Alternative Name: KCNJ3 (KCNJ3 Products)

Synonyms: GIRK1 antibody, KGA antibody, KIR3.1 antibody, Kcnf3 antibody, Kir3.1 antibody, girk1 antibody, potassium voltage-gated channel subfamily J member 3 antibody, potassium inwardly-rectifying channel, subfamily J, member 3 antibody, KCNJ3 antibody, Kcnj3 antibody

Background:

Background: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

Aliases: G protein activated inward rectifier potassium channel 1 antibody, G protein-activated inward rectifier potassium channel 1 antibody, GIRK-1 antibody, GIRK1 antibody, Inward rectifier K(+) channel Kir3.1 antibody, Inwardly rectifying potassium channel KIR3.1 antibody, inwardly rectifying subfamily J member 3 antibody, IRK3 antibody, IRK3_HUMAN antibody, Kcnf3 antibody, Kcnj3 antibody, KGA antibody, KGB1 antibody, Kir3.1 antibody, Potassium channel antibody, Potassium channel, inwardly rectifying subfamily J member 3 antibody, Potassium inwardly-rectifying channel, subfamily J, member 3 antibody

UniProt: P48549