NPPB antibody (C-Term)

Catalog No. ABIN4889378

The Rabbit Polyclonal anti-NPPB antibody has been validated for ELISA, WB, ICC and IF. It is suitable to detect NPPB in samples from Human and Monkey.

Quick Overview for NPPB antibody (C-Term) (ABIN4889378)

Target: NPPB (Natriuretic Peptides B (NPPB))

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPPB antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-NPPB Antibody

Binding Specificity: C-Term

Specificity: Reacts with human NPPB

Cross-Reactivity (Details): Cross react with monkeys protein due to sequence homology.

Purification: Purified (protein A)

Immunogen: Synthetic peptide of derived from C terminal part of human NPPB.

Application Details

Application Notes:

Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
- WB : 1/500 to 1/2000 - ICC, IF: 1/200 to 1/1000

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Concentration: 1 mg/mL

Buffer: Tris 0,1M, glycine 0,1M

Storage: 4 °C/-20 °C

Storage Comment: Short term storage at+4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 6 months

Target Details for NPPB

Target: NPPB (Natriuretic Peptides B (NPPB))

Alternative Name: NPPB

Background: Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.

Gene ID: 4879

UniProt: P16860

Pathways: Hormone Activity