PRNP antibody (Prion Protein) (C-Term)

Details for Product anti-PRNP Antibody No. ABIN4889437, Supplier: Log in to see
Antigen
  • ASCR
  • AltPrP
  • CD230
  • CJD
  • GSS
  • KURU
  • PRIP
  • PrP
  • PrP27-30
  • PrP33-35C
  • PrPc
  • p27-30
  • Prn
  • Prn-p
  • prp
  • cjd
  • prion
  • prp(c)
  • MGC84114
  • PRP
  • PRPC
  • Prp
  • SIP
  • PRNP
  • AA960666
  • AI325101
  • PrP
  • PrPC
  • PrPSc
  • Prn-i
  • Sinc
  • prP27-30
  • prP33-35C
  • PrP-1
  • PrP1
  • prnprs1
  • stPrP-1
  • zgc:123004
  • prion protein
  • prion protein S homeolog
  • prion protein b
  • PRNP
  • Prnp
  • prnp.S
  • prnpb
Alternatives
anti-Cow (Bovine) PRNP antibody for Enzyme Immunoassay
Epitope
C-Term
14
11
10
10
8
7
6
4
4
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Human, Rat (Rattus), Sheep (Ovine)
140
77
71
45
31
4
3
2
2
2
1
1
1
Host
Mouse
126
46
24
3
Clonality (Clone)
Monoclonal ()
Conjugate
This PRNP antibody is un-conjugated
9
8
6
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Application
ELISA, Immunofluorescence (IF), Western Blotting (WB)
150
81
62
42
26
20
11
9
8
7
5
4
4
Options
Supplier
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Immunogen A 15 residue synthetic peptide derived from C-terminal domain of human PrP protein
Clone 4H7
Isotype IgG2a kappa
Specificity Reacts with full sequence PrP protein of brain tissue from different species (bovin, human, sheep, rat
Cross-Reactivity Sheep (Ovine), Rat (Rattus)
Cross-Reactivity (Details) .) Cross reacts with brain tissue from different species (bovin, human, sheep, rat ...)
Purification Purified (protein A)
Plasmids, Primers & others Plasmids, Primers & others PRNP products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name Prion Protein (PrP) (PRNP Antibody Abstract)
Background PrP is found in high quantity in the brain of humans and animals infected with neurodegenerative diseases known as transmissible spongiform encephalopathies or prion diseases, like: Creutzfeldt-Jakob disease (CJD), fatal familial insomnia (FFI), Gerstmann-Straussler disease (GSD), Huntington disease-like type 1 (HDL1) and kuru in humans, scrapie in sheep and goat, bovine spongiform encephalopathy (BSE) in cattle.
UniProt P04156
Pathways Transition Metal Ion Homeostasis, Activated T Cell Proliferation
Application Notes

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
IF(1:200 - 1:1000) WB(1:200 - 1:1000)

Restrictions For Research Use only
Format Lyophilized
Reconstitution Must be reconstituted in distilled water.
Concentration 1 mg/mL
Buffer Tris 0,1M, glycine 0,1M, sucrose 2 %
Storage 4 °C/-20 °C
Storage Comment Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
Expiry Date 24 months
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