ATP1A1 antibody

Catalog No. ABIN4889534

The Mouse Monoclonal anti-ATP1A1 antibody is suitable to detect ATP1A1 in samples from Human, Rat, Mouse, Chicken and Zebrafish (Danio rerio). It has been validated for WB, IHC and IP.

Quick Overview for ATP1A1 antibody (ABIN4889534)

Target: ATP1A1 (Sodium Potassium ATPase, alpha1 (ATP1A1))

Reactivity: Human, Rat, Mouse, Chicken, Zebrafish (Danio rerio)

Host: Mouse

Clonality: Monoclonal

Conjugate: This ATP1A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Clone: A1F6

Product Details anti-ATP1A1 Antibody

Specificity: Reacts with N-terminal part of ATP1A1 protein from human, avain, mouse, rat, dog, pig, zebrafish

Cross-Reactivity: Sheep (Ovine)

Cross-Reactivity (Details): Weak or no binding to sheep and Xenopus proteins.

Purification: Purified (protein A)

Immunogen: Chicken Na+/K+ ATPase purified from kidney

Isotype: IgG2a kappa

Application Details

Application Notes:

Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only :
WB(1:10 - 1:1000)

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Concentration: 1 mg/mL

Buffer: Tris 0,1M, glycine 0,1M, sucrose 2 %

Storage: 4 °C/-20 °C

Storage Comment: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 24 months

Target Details for ATP1A1

Target: ATP1A1 (Sodium Potassium ATPase, alpha1 (ATP1A1))

Alternative Name: Sodium/potassium-Transporting ATPase Subunit alpha-1

Background: This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.

UniProt: P05023

Pathways: Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Proton Transport, Ribonucleoside Biosynthetic Process