YAP1 antibody

Catalog No. ABIN4889640

This anti-YAP1 antibody is a Mouse Monoclonal antibody detecting YAP1 in WB, IHC and IF. Suitable for Human.

Quick Overview for YAP1 antibody (ABIN4889640)

Target: YAP1 (Yes-Associated Protein 1 (YAP1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This YAP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: 12b4

Product Details anti-YAP1 Antibody

Specificity: Reacts with 53 kDa human Yorkie homolog YAP1

Purification: Purified

Immunogen: YAP1-GST tagged partial recombinant protein

Isotype: IgM

Application Details

Application Notes:

Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
WB : 1/500 to 1/5 000 IHC : 1/100 to 1/2 000 IF : 1/500 to 1/2000

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Concentration: 1 mg/mL

Buffer: Tris 0,1M, glycine 0,1M, sucrose 2 %

Storage: 4 °C/-20 °C

Storage Comment: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 24 months

Target Details for YAP1

Target: YAP1 (Yes-Associated Protein 1 (YAP1))

Alternative Name: Yorkie Homolog

Background: Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.

Gene ID: 10413

UniProt: P46937

Pathways: MAPK Signaling, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha