CD17 antibody

Catalog No. ABIN489936

The Mouse Monoclonal anti-CD17 antibody (Clone MEM-68) (ABIN489936) specifically detects CD17 in FACS. The antibody is reactive with Human samples.

Quick Overview for CD17 antibody (ABIN489936)

Target: CD17

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Flow Cytometry (FACS)

Clone: MEM-68

Product Details

Purpose: Anti-Hu CD17 Purified

Cross-Reactivity (Details): Human

Characteristics: The mouse monoclonal antibody MEM-68 recognizes CD17, an extracellular membrane lipid moiety lactosylceramide expressed on granulocytes, monocytes and platelets.

Purification: Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).

Purity: > 95 % (by SDS-PAGE)

Immunogen: Pre-B cell line NALM-6

Isotype: IgM

Application Details

Application Notes: Flow cytometry: Recommended dilution: 2 μg/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details

Target: CD17

Background: CD17, lactosylceramide, is an ubiquitous glycosphingolipid with uncharged disaccharide headgroup, highly enriched in lipid raft-derived structures. Besides playing a pivotal role in the biosynthesis of complex glycosphingilipids, lactosylceramide is involved in cell-cell and cell-matrix interactions and in signaling events linked to cell differentiation, development, apoptosis and oncogenesis. Lactosylceramide regulates integrin functions and production of nitric oxide. Its expression defines successive stages in the maturation of myeloid cells.,Lactosylceramide

Gene ID: 35