Cytochrome C antibody (AA 1-69)

Catalog No. ABIN4901338

This Rabbit Polyclonal antibody specifically detects Cytochrome C in WB and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Cytochrome C antibody (AA 1-69) (ABIN4901338)

Target: Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cytochrome C antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Cytochrome C Antibody

Binding Specificity: AA 1-69

Purpose: CYCS is a protein encoded by the CYCS gene which is approximately 11,7 kDa. CYCS is localised to the mitochondrion intermembrane space. It is involved in the TNFR1 pathway, respiratory electron transport and apoptosis modulation and signalling. It is a small heme protein that functions as a central component of the electron transport chain in the mitochondria. It associates with the inner membrane of the mitochondrion where it accepts electrons from cytochrome b and transfers them to the cytochrome oxidase complex. It is also involved in the initiation of apoptosis. CYCS is expressed in the nervous system, liver, kidney, heart and muscle. Mutations in the CYCS gene may result in thrombocytopenia. STJ98953 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This primary antibody detects endogenous CYCS.

Specificity: The antibody detects endogenous CYCS.

Characteristics: Rabbit Polyclonal to CYCS.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthetic peptide from human CYCS protein.

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000
ELISA 1:10000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for Cytochrome C

Target: Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

Alternative Name: CYCS

Molecular Weight: 15kDa

Gene ID: 54205

UniProt: P99999

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity