TUBE1 antibody

Catalog No. ABIN4901473

This Mouse Monoclonal antibody specifically detects TUBE1 in IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TUBE1 antibody (ABIN4901473)

Target: TUBE1 (Tubulin, epsilon 1 (TUBE1))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This TUBE1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 3G1

Product Details anti-TUBE1 Antibody

Purpose: Epsilon tubulin is a protein encoded by the TUBE1 gene which is approximately 52,9 kDa. Epsilon tubulin is localised to the cytoplasm and cytoskeleton. It is involved in Sertoli-Sertoli cell junction dynamics, the PAK pathway, G-beta gamma signalling and ERK signalling. This protein falls under the tubulin superfamily. It localizes to the centriolar sub-distal appendages that are associated with the older centriole after centrosome duplication and plays a central role in organization of the microtubules during centriole duplication. Epsilon tubulin is expressed in the cells of the nervous system. Mutations in the TUBE1 gene may result in chronic frontal sinusitis. STJ97751 was developed from clone 3G1 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This primary antibody detects endogenous levels of epsilon tubulin.

Specificity: Epsilon Tubulin Mouse Monoclonal Antibody (3G1) detects endogenous levels of Epsilon Tubulin

Characteristics: Mouse Monoclonal to Epsilon Tubulin.

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Immunogen: synthetic peptide derived from Epsilon Tubulin

Isotype: IgG1

Application Details

Application Notes: IHC 1:100-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for TUBE1

Target: TUBE1 (Tubulin, epsilon 1 (TUBE1))

Alternative Name: Epsilon Tubulin

Gene ID: 51175

UniProt: Q9UJT0

Pathways: Microtubule Dynamics