NBR1 antibody

Catalog No. ABIN4901991

The Mouse Monoclonal anti-NBR1 antibody (ABIN4901991) specifically detects NBR1 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for NBR1 antibody (ABIN4901991)

Target: NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This NBR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-NBR1 Antibody

Purpose: NBR1 is a protein encoded by the NBR1 gene which is approximately 107,4 kDa. NBR1 is localised to the cytoplasm and is involved in animal mitophagy. It contains a B-box/coiled-coil motif and functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. NBR1 is expressed in the nervous system, bone marrow, lung and muscle. Mutations in the NBR1 gene may result in inclusion body myositis and synucleinopathy. STJ98902 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This primary antibody detects endogenous NBR1 protein.

Specificity: The antibody detects endogenous NBR1 protein.

Characteristics: Mouse Monoclonal to NBR1.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Recombinant peptide derived from NBR1.

Application Details

Application Notes: WB 1:500-2000
ELISA 1:10000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for NBR1

Target: NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))

Alternative Name: NBR1

Molecular Weight: 120kDa

Gene ID: 4077

UniProt: Q14596

Pathways: Autophagy