PTK2B antibody

Catalog No. ABIN4902194

The Mouse Monoclonal anti-PTK2B antibody has been validated for WB. It is suitable to detect PTK2B in samples from Human, Mouse, Dog, Rabbit and Pig.

Quick Overview for PTK2B antibody (ABIN4902194)

Target: PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))

Reactivity: Human, Mouse, Dog, Rabbit, Pig

Host: Mouse

Clonality: Monoclonal

Conjugate: This PTK2B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PTK2B Antibody

Purpose: Mouse monoclonal to PYK2.

Specificity: PYK2 Monoclonal Antibody detects endogenous levels of PYK2 protein.

Characteristics: Mouse Monoclonal to PYK2.

Purification: Affinity purification

Immunogen: Purified recombinant human PYK2 protein fragments expressed in E.coli.

Application Details

Application Notes: WB 1:1000-1:2000

Comment:

Most abundant in the brain, with highest levels in amygdala and hippocampus. Low levels in kidney (at protein level). Also expressed in spleen and lymphocytes.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (  pH 7.4, 150 mM NaCl) with 0.2 % sodium azide, 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for PTK2B

Target: PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))

Alternative Name: PYK2

Gene ID: 2185

UniProt: Q14289

Pathways: EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Cellular Glucan Metabolic Process, Cell-Cell Junction Organization, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Positive Regulation of fat Cell Differentiation, VEGF Signaling