CD40 Ligand antibody

Catalog No. ABIN490311

The Hamster Monoclonal anti-CD40 Ligand antibody (Clone MR1-MR-1) (ABIN490311) specifically detects CD40 Ligand in FACS, IHC, IP, ICC, Func, BR and Neut. The antibody is reactive with Mouse samples.

Quick Overview for CD40 Ligand antibody (ABIN490311)

Target: CD40 Ligand (CD40LG)

Reactivity: Mouse

Host: Hamster

Clonality: Monoclonal

Conjugate: This CD40 Ligand antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC), Functional Studies (Func), Blocking Reagent (BR), Neutralization (Neut)

Clone: MR1-MR-1

Product Details anti-CD40 Ligand Antibody

Specificity: The hamster monoclonal antibody MR-1 detects mouse CD154 / CD40L (CD40-ligand), a 39 kD cell surface glycoprotein expressed predominantly on activated CD4+ lymphocytes.

Purification: Protein A purified

Immunogen: Activated mouse Th1 clone D1.6.

Type of Immunogen: Cells

Isotype: IgG1

Application Details

Application Notes: Approved: Block, Flo, Func, ICC, IHC, IP, Neut

Usage: Flow Cytometry: Recommended dilution - 4 μg/mL. Positive control - 6-8 hour activated mouse splenocytes. Functional Application: Blocking T cell costimulation in vivo.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 15 mM sodium azide,  pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Target Details for CD40 Ligand

Target: CD40 Ligand (CD40LG)

Alternative Name: CD40L

Background: Name/Gene ID: CD40LG
Family: TNF

Synonyms: CD40LG, CD154, CD154 antigen, CD40-L, CD40 ligand, CD40L, gp39, HIGM1, IGM, IMD3, T-BAM, TNFSF5, CD40 antigen ligand, CD54, HCD40L, T-B cell-activating molecule, T-cell antigen Gp39, TNF-related activation protein

Gene ID: 959

Pathways: NF-kappaB Signaling, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints