Calpain 2 antibody

Catalog No. ABIN4907387

The Mouse Monoclonal anti-Calpain 2 antibody has been validated for WB, IHC (p) and FACS. It is suitable to detect Calpain 2 in samples from Human and Mouse.

Quick Overview for Calpain 2 antibody (ABIN4907387)

Target: Calpain 2 (CAPN2)

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Calpain 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: 1C1

Product Details anti-Calpain 2 Antibody

Cross-Reactivity: Human, Mouse

Purification: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This CAPN2 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between amino acids from the human region of human CAPN2.

Isotype: IgG2b

Application Details

Application Notes: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for Calpain 2

Target: Calpain 2 (CAPN2)

Alternative Name: CAPN2

Background:

Synonyms: CANP2, mCANP, CANPL2, CANPml, Calpain-2 catalytic subunit, Calcium-activated neutral proteinase 2, CANP 2, Calpain M-type, Calpain large polypeptide L2, Calpain-2 large subunit, Millimolar-calpain, M-calpain, CAPN2

Background: Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' (PubMed:17650508).

Gene ID: 824

UniProt: P17655