CD40 antibody (C-Term)

Catalog No. ABIN4907736

The Mouse Monoclonal anti-CD40 antibody (Clone 7C4) (ABIN4907736) specifically detects CD40 in WB. The antibody is reactive with Human samples.

Quick Overview for CD40 antibody (C-Term) (ABIN4907736)

Target: CD40

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD40 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 7C4

Product Details anti-CD40 Antibody

Binding Specificity: AA 247-276, C-Term

Purpose: CD40 (7C4) Monoclonal Antibody

Cross-Reactivity: Human

Purification: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogen: This CD40 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 247-276 amino acids from the C-terminal region of human CD40.

Isotype: IgG1

Application Details

Application Notes: WB(1:300-5000)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin, Sodium azide

Precaution of Use: This product contains ProClin and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for CD40

Target: CD40

Alternative Name: CD40

Background:

Synonyms: p50, Bp50, CDW40, TNFRSF5, Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, CD40L receptor, CD40

Background: Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.

Gene ID: 958

UniProt: P25942

Pathways: NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints