DAB2IP antibody (AA 782-1038)

Catalog No. ABIN4908550

This Mouse Monoclonal antibody specifically detects DAB2IP in WB. It exhibits reactivity toward Human.

Quick Overview for DAB2IP antibody (AA 782-1038) (ABIN4908550)

Target: DAB2IP (DAB2 Interacting Protein (DAB2IP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DAB2IP antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 6C1

Product Details anti-DAB2IP Antibody

Binding Specificity: AA 782-1038

Purpose: DAB2IP (6C1) Monoclonal Antibody

Cross-Reactivity: Human, Mouse

Purification: Purified by Protein G.

Immunogen: This DAB2IP antibody is generated from a mouse immunized with a recombinant protein between 782-1038 amino acids from human DAB2IP.

Isotype: IgG2a

Application Details

Application Notes: WB(1:300-5000)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for DAB2IP

Target: DAB2IP (DAB2 Interacting Protein (DAB2IP))

Alternative Name: DAB2IP

Background:

Synonyms: AIP1, AIP-1, AF9Q34, DIP1/2, Disabled homolog 2-interacting protein, DAB2 interaction protein, DAB2-interacting protein, ASK-interacting protein 1, DOC-2/DAB-2 interactive protein, DAB2IP, KIAA1743

Background: DAB2IP is a Ras (MIM 190020) GTPase-activating protein (GAP) that acts as a tumor suppressor. The DAB2IP gene is inactivated by methylation in prostate and breast cancers (Yano et al., 2005 [PubMed 15386433]).[supplied by OMIM, May 2010]

Gene ID: 153090

UniProt: Q5VWQ8

Pathways: EGFR Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Tube Formation