FGG antibody

Catalog No. ABIN4909566

This anti-FGG antibody is a Mouse Monoclonal antibody detecting FGG in WB. Suitable for Human.

Quick Overview for FGG antibody (ABIN4909566)

Target: FGG (Fibrinogen gamma Chain (FGG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FGG antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 6C3

Product Details anti-FGG Antibody

Cross-Reactivity: Human

Purification: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogen: This FGG antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 417-445 amino acids from human FGG .

Isotype: IgG1

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for FGG

Target: FGG (Fibrinogen gamma Chain (FGG))

Alternative Name: FGG

Background:

Synonyms: Fibrinogen gamma chain, FGG, PRO2061

Background: Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.

Gene ID: 2266

UniProt: P02679