ITGA6 antibody

Catalog No. ABIN4911222

The Mouse Monoclonal anti-ITGA6 antibody (Clone 9C5) (ABIN4911222) specifically detects ITGA6 in WB, FACS, IF and IHC (p). The antibody is reactive with Human samples.

Quick Overview for ITGA6 antibody (ABIN4911222)

Target: ITGA6 (Integrin, alpha 6 (ITGA6))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ITGA6 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 9C5

Product Details anti-ITGA6 Antibody

Purpose: ITA6 (9C5) Monoclonal Antibody

Cross-Reactivity: Human

Purification: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: ITA6 recombinant protein is used to produce this monoclonal antibody.

Isotype: IgG1

Application Details

Application Notes: WB(1:300-5000), FCM(1:200-400), IHC-P(1:200-400), IF()

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin, Sodium azide

Precaution of Use: This product contains ProClin and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for ITGA6

Target: ITGA6 (Integrin, alpha 6 (ITGA6))

Alternative Name: ITA6

Background:

Synonyms: CD49f, VLA-6, ITGA6B, Integrin alpha-6, CD49 antigen-like family member F, ITGA6

Background: Integrin alpha-6/beta-1 is a receptor for laminin on platelets. Integrin alpha-6/beta-4 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome (By similarity). ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:22351760).

Gene ID: 3655

UniProt: P23229

Pathways: CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex