TIMP2 antibody

Catalog No. ABIN4914666

The Mouse Monoclonal anti-TIMP2 antibody (Clone 4C7) (ABIN4914666) specifically detects TIMP2 in WB, IF, IHC (p), FACS and IF (cc). The antibody is reactive with Human samples.

Quick Overview for TIMP2 antibody (ABIN4914666)

Target: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TIMP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))

Clone: 4C7

Product Details anti-TIMP2 Antibody

Purpose: TIMP-2 (4C7) Monoclonal Antibody

Cross-Reactivity: Human

Purification: Purified by Protein G.

Immunogen: This TIMP2 antibody is generated from a mouse immunized with arecombinant protein of human TIMP2.

Isotype: IgG1

Application Details

Application Notes: WB(1:300-5000), FCM(1:20-100), IHC-P(1:200-400), IF(ICC)(1:50-200), IF()

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for TIMP2

Target: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Alternative Name: TIMP2

Background:

Synonyms: DDC8, CSC-21K, Metalloproteinase inhibitor 2, Tissue inhibitor of metalloproteinases 2, TIMP-2, TIMP2

Background: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.

Gene ID: 7077

UniProt: P16035

Pathways: cAMP Metabolic Process