IBSP antibody (AA 108-122)

Catalog No. ABIN492661

This Mouse Monoclonal antibody specifically detects IBSP in EIA. It exhibits reactivity toward Human.

Quick Overview for IBSP antibody (AA 108-122) (ABIN492661)

Target: IBSP (Integrin-Binding Sialoprotein (IBSP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IBSP antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Clone: 243 8B1

Product Details anti-IBSP Antibody

Binding Specificity: AA 108-122

Specificity: Recognizes Carbohydrate-deficient Bone Sialoprotein (CD-BSB/Tumor-BSP).

Characteristics: Synonyms: Bone sialoprotein II, BSP II, IBSP, BNSP, Cell-binding sialoprotein, Integrin-bindingsialoprotein

Purification: Protein G Chromatography

Immunogen: Recombinant Human CD-BSP

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/2000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore in aqua bidest to 1 mg/mL

Buffer: PBS, pH 7.4

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2-8 °C and reconstituted at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch.

Expiry Date: 12 months

Target Details for IBSP

Target: IBSP (Integrin-Binding Sialoprotein (IBSP))

Alternative Name: Bone Sialoprotein 2

Background: The protein encoded by the Bone Sialoprotein gene is a major structural protein of the bone matrix. It is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts, and it constitutes approximately 12 % of the noncollagenous proteins in human bone. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor.Synonyms: BNSP, BSP II, Bone sialoprotein II, Cell-binding sialoprotein, IBSP, Integrin-binding sialoprotein

Gene ID: 3381

UniProt: P21815