BAFF antibody
Quick Overview for BAFF antibody (ABIN4949453)
Target
See all BAFF (TNFSF13B) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Grade
Clone
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Purpose
- BAFF Antibody / BLyS (azide and preservative free)
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Purification
- Protein G affinity chromatography
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Immunogen
- Recombinant human BAFF protein was used as the immunogen for this BAFF antibody.
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Isotype
- IgG1, kappa
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anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) (AA 116-278) antibody
TNFSF13B Reactivity: Human WB, ELISA, FACS, ICC Host: Mouse Monoclonal 6C3A2 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) (AA 221-309) antibodyTNFSF13B Reactivity: Human, Rat ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) (AA 1-285) antibodyTNFSF13B Reactivity: Human WB, ELISA, IP Host: Mouse Monoclonal 2C11 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) (AA 76-285) antibodyTNFSF13B Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) (AA 118-222) antibodyTNFSF13B Reactivity: Human WB, ELISA, IP Host: Mouse Monoclonal 3G6 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) (AA 134-285) antibodyTNFSF13B Reactivity: Human ELISA, FACS, ICC, IF Host: Mouse Monoclonal H4-C7 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) (AA 16-44), (N-Term) antibodyTNFSF13B Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB33784 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) antibodyTNFSF13B Reactivity: Human WB, FACS, IHC (p) Host: Mouse Monoclonal 1D6 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) (AA 45-169) antibodyTNFSF13B Reactivity: Rat WB, IHC, IP, IF/ICC Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) (AA 265-285) antibodyTNFSF13B Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
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Application Notes
- Titering of the BAFF antibody may be required for optimal performance.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Preservative
- Azide free
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Storage
- 4 °C,-20 °C
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Storage Comment
- BAFF antibody with azide can be stored at 2-8oC. The azide-free format should be aliquoted and stored at -20oC or colder.
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- BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))
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Alternative Name
- BAFF
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Background
- BAFF/BLyS/CD257 is a type II transmembrane protein, and a member of the tumor necrosis factor ligand superfamily. It is proteolytically cleaved to form a soluble protein. BAFF, like other TNF ligand family members, forms homo-trimers. The predicted molecular weight of a BAFF monomer is approximately 31 kDa. It is expressed on peripheral blood B and T lymphocytes, monocytes, macrophages, and dendritic cells and is upregulated by IFN-γ, and down-regulated by PMA/ionomycin treatment. BAFF stimulates B and T cell immunity and regulates humoral immunity by binding TACI and BCMA receptors, BAFF prevents apoptosis and promotes B cell survival by binding the BAFF-specific receptor (BAFFR/BR3).
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UniProt
- Q9Y275
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Pathways
- NF-kappaB Signaling, Production of Molecular Mediator of Immune Response
Target
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